Nanotechnology in Bone Tissue Engineering

Nanotechnology is currently being utilized for regenerative medicine and tissue engineering. Nanotechnology represents a major frontier with potential to significantly advance in the field of tissue engineering. Nanotechnology can be used to create nanopatterns, controlled release nanoparticles and nanofibers with application in tissue engineering, for mimicking native tissues since biomaterials to be engineered is of nanometre size like extracellular fluids, cardiac tissues and bone marrow etc. in this technology several major areas of research in bone regeneration: 1) nanoparticle-based methods for delivery of bioactive molecules, growth factors, and genetic material, 2) nanoparticle-mediated cell labeling and targeting and 3) Nano based scaffold construction and modification to enhance physiochemical interaction, mechanical stability. Nanotechnology is the ultimate translation to the clinical environment it will be allow for the improvement of therapeutic outcomes in patients with large bone deficits and osteodegenerative diseases.

  • Cell seeding
  • Nanocomposite approaches
  • Nanoparticle mediated cell targeting
  • Nanopattern
  • Beaded Nanofibers
  • Electrospinning

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